KETAMINE'S EFFECT ON DEPRESSION

Ketamine is a medication that has been used as an anesthetic for many years.  However, more recently, it has been found to have rapid and effective antidepressant effects, particularly in treatment-resistant depression.  The exact mechanism by which ketamine helps depression is not fully understood, but research suggests that is works by modulating the activity of certain neurotransmitters in the brain, particularly glutamate. 

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WHICH METHOD OF KETAMINE DELIVERY IS MOST EFFECTIVE?

I frequently get asked “which method of ketamine delivery is the most effective?  Intravenous (IV), a shot into the muscle (IM) or nasal spray?”

Both intravenous (IV) and intramuscular (IM) ketamine and nasal spray have been sued to treat depression, although IV ketamine is generally considered the gold standard due to its faster onset and more consistent dosing.

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WHAT DOES A KETAMINE INFUSION FEEL LIKE?

I frequently get asked the question “what does a ketamine infusion feel like?”

Ketamine is a dissociative anesthetic that has been used for decades in the medical setting. It is known for its ability to produce an altered state of consciousness and has gained popularity in the treatment of mood disorders such as depression, anxiety and PTSD. Getting a ketamine infusion allows for a patient to receive a dose of ketamine that is highly individualized and the doctor can maintain a desired blood level for as long as needed, usually 40 minutes.

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