7-OH Addiction Treatment

What is 7-OH (7-Hydroxymitragynine)?

7-OH, short for 7-hydroxymitragynine, is a compound found naturally in the kratom plant in very small amounts. Recently, highly concentrated 7-OH products have become increasingly available in forms such as tablets, powders, drink mixes, shots, and extracts.

These concentrated products are very different from traditional kratom leaf. 7-OH acts on opioid receptors in the brain and can produce powerful opioid-like effects. With repeated use, some people develop tolerance, cravings, physical dependence, and withdrawal when they try to stop.

Can You Become Dependent on 7-OH?

Yes. People who use concentrated 7-OH regularly may find themselves needing larger or more frequent doses to achieve the same effect or simply to avoid feeling sick.

Dependence can sometimes develop before a person realizes how difficult stopping 7-OH may be.

7-OH (7-hydroxymitragynine) dependence withdrawal and addiction treatment information

What Does 7-OH Withdrawal Feel Like?

People who become physically dependent on 7-OH may experience withdrawal when they reduce their dose or stop using it. Because 7-OH acts on opioid receptors, withdrawal can resemble opioid withdrawal.

Symptoms may include:

  • Anxiety or restlessness

  • Body Aches

  • Sweating or chills

  • Difficulty sleeping

  • Nausea, vomiting, or diarrhea

  • Abdominal cramping

  • Irritability

  • Fatigue

  • Strong cravings

The severity and duration of withdrawal can vary depending on how much 7-OH a person uses, how frequently they use it, how long they have been using it, and whether other substances are involved.


How is 7-OH Dependence Treated?

There is currently no FDA-approved medication specifically for 7-OH dependence. Because 7-OH has opioid-like effects, treatment may include medical evaluation, withdrawal management, counseling, and medications that are commonly used to treat opioid use disorder when clinically appropriate.

Buprenorphine is an FDA-approved medication for opioid use disorder, and emerging medical literature has described its use in patients with problematic 7-OH use and withdrawal. Treatment should be individualized based on the patient’s symptoms, pattern of use, medical history, and other substances or medications involved.

Tidewater Health provides confidential telehealth evaluations for patients throughout South Carolina who are struggling with 7-OH, kratom or opioid dependence.

What Can I Expect From Treatment at Tidewater Health:

Your first appointment is a confidential telehealth visit with our Medical Director who will talk with you about your 7-OH use, withdrawal symptoms, medical history, medications, and treatment goals.

If treatment is appropriate, an individualized plan will be developed to help manage withdrawal and cravings and support your recovery.

Follow-up appointments are also provided through secure telehealth, allowing you to receive ongoing care from the privacy of your home.

Tidewater Health treats eligible patients throughout South Carolina, so there is no need to travel to an office for routine appointments.

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Frequently Asked Questions About 7-OH

Is 7-OH the same as kratom?

Not exactly. 7-OH (7-hydroxymitragynine) occurs naturally in the kratom plant in very small amounts. However concentrated 7-OH products can contain much higher levels than traditional kratom leaf and may produce stronger opioid-like effects.

Can 7-OH cause dependence and withdrawal?

Yes. Regular use of concentrated 7-OH can lead to tolerance and physical dependence. People who stop or significantly reduce their use may experience withdrawal symptoms such as anxiety, restlessness, body aches, sweating, gastrointestinal symptoms, difficulty sleeping, and cravings.

Can buprenorphine be used to treat 7-OH dependence or withdrawal?

There is currently no FDA-approved medication specifically for 7-OH dependence. However, emerging medical literature has described the use of buprenorphine in patients experiencing problematic 7-OH use and withdrawal. A medical provider should evaluate each patient individually to determine whether medication-assisted treatment is appropriate.

Can I get treatment for 7-OH online in South Carolina?

Tidewater Health provides secure telehealth evaluation and addiction treatment for eligible patients throughout South Carolina. Your provider will evaluate your 7-OH use, symptoms, medical history, medications, and individual treatment needs to determine an appropriate plan.

How do I get started?

Call or text 843-990-8547 or complete the online submission form. Your initial appointment is completed through secure telehealth from the privacy of your home.